The overdue promise of short tandem repeat variation for heritability
نویسندگان
چکیده
منابع مشابه
The overdue promise of short tandem repeat variation for heritability.
Short tandem repeat (STR) variation has been proposed as a major explanatory factor in the heritability of complex traits in humans and model organisms. However, we still struggle to incorporate STR variation into genotype-phenotype maps. We review here the promise of STRs in contributing to complex trait heritability and highlight the challenges that STRs pose due to their repetitive nature. W...
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in the present study, genotyping of six short tandem repeat (str) loci including csf1po, d16s539, f13a01, f13b, lpl and hprtb was performed on genomic dna from 127 unrelated individuals from the iranian province of isfahan. the results indicated that the allele and genotype distributions were in accordance with hardy-weinberg expectations. the observed heterozygosity (ho), expected heterozygosi...
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ژورنال
عنوان ژورنال: Trends in Genetics
سال: 2014
ISSN: 0168-9525
DOI: 10.1016/j.tig.2014.07.008